We have a professional team to manipulate Fluorination reactions with more than 30 years experiences. Now we have the technology to use anhydrous HF, KF, F2, SF4, CF2=CF2, CF3CH=CH2 and various fluorinated reagents as the fluorinating agents to introduce (F)x to organic-compounds and a number of functional groups into fluorinated molecules. If you want to avoid Fluorination reactions in your research and development laboratories due to safety concerns or haven’t the expensive equipment for a small scale Fluorination reaction, the Sinofluoro team who are dedicated to fluorochemistry are able to carry out a whole range of conversions from grams to tons scales.

Examples of site-selective fluorination

• 1.Fluorine(F2)

• 2.Sulfur tetrafluoride(SF4)

3.Nucleophilic Fluorinations:

F-= BrF3, HF, IF5, Deoxofluor, DAST, MOST, DFI, Et3N.3HF…

4.Electrophilic Fluorinations:

Nu-=nuclephine, XNF=souce of F+, for example, NFSI, SelectfluorTM, NFPY…

5. Schiemann " Reaction

6. Finkelstein" Reaction

7. Nucleophilic Substitution Cl (Br) or NO2 → F (KF, NaF, CoF3)


8. Methods for Introduction of CFn–Group(n=1,2,3):